Casa Grande, AZ distance to major western cities. Hover over cities to see distance. San Diego 352 Miles and available by rail Los Angeles is 424 Miles Phoenix is 51 Miles Nogales is 128 Miles Las Vegas is 346 Miles Salt Lake City is 710 Miles Denver is 869 Miles Albuquerque is 455 Miles El Paso is 395 Miles Tucson is 63 Miles Casa Grande is at the crossroads of two major interstates and the Union Pacific railroad. This makes it a prime location for industry, manufacturing and distribution.